Cloned (Comment) | Organism |
---|---|
gene tetH, genes tetH and doxD2 act synergistically, and doxD2 is considered important in thiosulfate metabolism, quantitative reverse transcription-PCR analysis | Acidithiobacillus ferrooxidans |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a tetH knockout mutant DELTAtetH and a tetH overexpression strain, the tetH overexpression strain grows better on sulfur and tetrathionate and possesses a higher rate of tetrathionate utilization and TetH activity than the wild-type. The DELTAtetH mutant cannot grow on tetrathionate but can proliferate on sulfur with a lower cell yield than the wild type | Acidithiobacillus ferrooxidans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acidithiobacillus ferrooxidans | B7J3C9 | gene tetH | - |
Synonyms | Comment | Organism |
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Teth | - |
Acidithiobacillus ferrooxidans |
General Information | Comment | Organism |
---|---|---|
malfunction | the DELTAtetH mutant can survive in ferrous medium with an Fe2+ oxidation rate similar to that of the wild-type. For the tetH overexpression strain, the rate is relatively higher than that of the wild type | Acidithiobacillus ferrooxidans |
metabolism | the organism can obtain energy from the oxidation of Fe2+, H2, and sulfur, and various reduced inorganic sulfur compounds (RISCs). Tetrathionate is a key intermediate during RISC oxidation, hydrolyzed by tetrathionate hydrolase (TetH), and used as sole energy source. Genes tetH and doxD2 act synergistically, and doxD2 is considered important in thiosulfate metabolism | Acidithiobacillus ferrooxidans |
physiological function | the enzyme is a key enzyme in hydrolysis of tetrathionate for usage as sole energy source | Acidithiobacillus ferrooxidans |